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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3edbcb7d317b2357f3821020056e2e70d91a34133f992b25dda6d8a3a1df33' 
  AND token = 'YphxNSM9y4VLS0QOPcTOsPKgaHWdcYX+o2HybSE6ZdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}