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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ac3a9a582f4e908dace1a96b198ed5ee9edef5c3d67f514efd5d1499c7bc07' 
  AND token = 'lRgkRj+9G05lJjjA04pYLb92WUudZAFfbvpA0uJWZpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}