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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810317b6e369bb3bb06702212ae973f85df342b149dfce736e81ee99859c7320' 
  AND token = 'Oa7CsMFDN75whkenh3lyQ2sS1oDZNHOYzpqtvTtsnYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}