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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1497d0514dc27ae0b0eba1d5db47a6d8072fc1a3da5467ae44084780ed287486' 
  AND token = 'QZ0p4PLwGCamfFgXkGMOns8txewt42+WvwfQ96T5VCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}