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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b092449f6abe0cb578084c200e52be4d4e7449ac2d02542b019168102603f36' 
  AND token = 'EZAIan6K20uhfCLoqIxduqPL2roIRJY62DoCzDfOy7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}