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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c33a2f8a1dfc87e9d5ccdfa505fa4be11b8428b84299f3c7553d76efd53de43' 
  AND token = 'B4KRnde4o6ClxsRChyw7qHdkipG3GqxGJYH9KDpWk1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}