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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de1d61ddda142a56d014797680b37d9ef060481c912652718db23743cf3b4d9' 
  AND token = '8w7MHD45rvzKeIe/oI0NDz46vMmUnDzchr7JsstZuJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}