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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0602dc6673e43bfb2d845de902778b41e9d11f1a534de3d865bfbc3c5d45d3' 
  AND token = 'J9dNQHv+tRkFUT35+s+yik9Qyt5hrcOAJhvFpkoMyws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}