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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac369928e6806b6a3e4ec6a8702bb081f22da83af6c56da7aff44c572425620d' 
  AND token = '+D28BFLt5sL1dQUF7wMjiDzDbETpg4RQGbDKdTc0vQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}