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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005d7f9d000116e69dc78a5d186cf49bfd3d8d71b875c41ccbe538317e4e8539' 
  AND token = '5h3pCd9k0RYF0VVH1YlS1rIbfzNfy3o2oDcr9deKohA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}