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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f18d53b8cf7b0f47b577e7d4b22350c2e0831671c8d080466700581c8582212' 
  AND token = 'VLxvVFq05zVprPLlM5/XMWvNioWBdDPdDEVrm9W4DOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}