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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2322550c823b47b83c832fb8d8a5e259d2e242d8860e9d8e83ee5cee55c911' 
  AND token = 'iQKNbRHNNecaMIqVNiMnJErc1HD1iqmatArav1Z3QIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}