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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650afd288e96860512eeb6ec3b7b2b06befad171f0c2a73853956b72088a8c64' 
  AND token = 'kXfwTT9FI2XHZl2wLxpLPKeioXb4DdWPSvuSujXPp7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}