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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e35586893aa8bbb2ceec9fd72d2b2794e6d158d77c8b67faa1597fd5c3fc242' 
  AND token = 'k0J6+GOroQeS3GQ6VayhKURneEBR/VrAdvlyuBIQYoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}