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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbbcb0e8b1458a44d104a0012ec913238bacd860a4918d5dc1c197d5d3c3051' 
  AND token = 'w7+lpXQ28Cdk0oxIG58658RPjCwjirhNwFYPjYav5nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}