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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a11b9213bddbdd8fa35f0c6b54ed5b2152328c94e9f5c123f1955523c984360f' 
  AND token = '+mSislm/5jgiQbc+ObWGDumXlhyL4VwUEUSpnfdVlCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}