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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd736b3e5dfbbcd308f4b1dbd69cf314a7426296a50ed6da76c14c56688f20542' 
  AND token = 'ZR9DnS6Wrutp0wdGKyF+QHVbvRvx8SM0du6jfnfOyBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}