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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8560482d1dd77bb9aaf8b058978cba0fa746c55562b6613270bcb5559026b7' 
  AND token = 'ettlYy72q1AnEGaAt+oRc3tJifnZlrLRVnYzTgZm4b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}