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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21612a095b0ad2f9560a2a64c436bda94e7cac978bfb34c41dae577438f2f5eb' 
  AND token = 'UFnqQvw/oNql4YPL5KiNrD58t/P9g8/lO6rZ49p2o0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}