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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493727bae3c5c1369ee2e2f7f9a7d5356750b989c91986e46d732a6f27db0ee5' 
  AND token = 'HSO2a/k0kUxxHZsyCzAor1SSJe92TO1dlFhRVkPPWNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}