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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c486449bc92a7a2f6c743c09b98b3c5af7e80e6725582f1b980f29754f46d0c0' 
  AND token = 'tRWodPnUicMTfUHPo1uXahDZsaC+GsggFrusnpJp1S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}