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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53130ccf2a11888182a9c0770ca890aad4b646323848a07319290e9217506be7' 
  AND token = 'SUfKWaJblxqZNYxfSOPmOmFiX0o4CxteUv/9OLeKSCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}