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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c486025202a766a74a56177b7c892a91f847feec277843aa67dcc6f769b08ed2' 
  AND token = '6Gj0OXJh6NifoFtkjqQYCQMrGze0APFWl3uf+ESey+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}