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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa791fcc3b3fea90ef7722724b4a05b865d7c931b5fb6cc68388aacebb27c4e' 
  AND token = 'I4gy3F/VoFUe5acg2ZNcSsPFCYuXnz9qWSRX0qIogp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}