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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c70bfb5a2ecab585e3f98335e1ddc018b58165df659b8e27017731db8fd187c' 
  AND token = 'NEE9h7snPN//LMrZx4Tdc14xhTPhVCOm3ETAR5j7cvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}