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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91525208d304a83f7952ce1f22262d3de05729b7c8722bf7b56c53f3f4e84a62' 
  AND token = 'WFiBeU5zTNUa9oLqRIES9f/0OOqpWmkNYWSvphGnuUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}