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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a338096f4cc3c89d9da4292da3397f73e1149f88a515f7aaf637c999cd1a760' 
  AND token = 'Ibk8Q7wTWeCM835FlTokmVbK9FVVUDQG64mz+LKa8v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}