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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25f34e4f8d41699455dd91120cbcce5f6d445fcbb675ec539ef38050e70fb2c' 
  AND token = '/He1YLmRE5qF2e549UyRpzAX7wTG+FNLfXUwegy8Rpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}