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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1349f2d6a6abc55b5f412313b76c40afb906eb0d9a2b5c4f11d0b62ff6f46d' 
  AND token = 'vRy2IH8hmzYPu90kh+sUW71Tid7cHgNLG9w5DaqAA4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}