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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1712630ad8279ac93bd2a5b093dfcfca4b421e4acdc460d0a95646e5c3a6ce' 
  AND token = 'Lrr5EzyZhHiVCbQzg07DgW20ibADDHnFzLrluYPlo3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}