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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3a6777dbe2f7d8bb050e32260eaed4a58d64f5048325fcc6a792d04c31c27e' 
  AND token = 'c6yoWQPArLY6G1udIaWG2iKnkVQgc2jJ1TtVyInuveM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}