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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d86c24af3b76dbb88aa524819a254e8faae51a929e0c8588bf770ec6c2ecaab' 
  AND token = 'hVQ0WpnMziu1oyAZ3MDoVrGALkPJo5OHrXjDOqsD1q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}