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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e11adc5040c2b46e8589f19cf096462119e6d2104dcf0cc22973b710bd20f95f' 
  AND token = 'Zt23ah3UPotMeWY1yFHZ2VpBK4U3cY3U/7P+xmrWhZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}