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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cd2a197055ff48920366a70dde53230ef34aebfe320f2f5d92bdda6bf384a8' 
  AND token = 'UoyqxO4iM/LKES2ztWUTDxXDs5j0GducfYl6xvzr9RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}