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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92287ed05f7c2de743fd0b9f7eb9effbcdaa2bee6e1ff95472a656f561af5a93' 
  AND token = 'AUfB5n3nJqwptGsSYYfLSkROi0kWHjjZbyP43O1Ng3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}