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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfc7cab895e841152d1c6e8cc681a05a379f073d592d8bfb87751eed108be230' 
  AND token = 'ovpo+kydoShG4KeZFyx1431TbTFlVP00iLBHBMTvncA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}