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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c7b04a4b37d3abdda6d2a8a7d2f772205fc30b5362708b92a4447c512a49c45' 
  AND token = '+4+TLYE8eAZtLHalfQVO3FShbABP9Naq+VVG/9gJSAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}