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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d21621fceba90e889b2674d3a0f94e2505d3a19d17c0afeffe462cb87010bd' 
  AND token = 'h1wrMP3sf9rlBalMuMBuXjAkQAdomhZ4YuNDPbXTKu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}