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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9466a5c4551bdf07141858a12d478cf4077c0945f5e0d46be2ba3d6da853e9c' 
  AND token = 'x+QMxQnjPZrwgPC6Dw/avtW6xlalHinB3M6I81PI7Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}