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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5256d1d39f330dab61724c106e218f841760f8173c7fff34290426b75d4ef009' 
  AND token = 'U8tM2Qn0ECqfBUht/7wMzM6hgrVGMQliPkllJGi0VUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}