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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cacf83fb9a21c75541486ff0bf60c466c5ec1d35a4942d78e224b699f2a7bba' 
  AND token = 'RXydLQYO5RYrCx/3HTMzetmYm7FecZoC19xcPRQIfUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}