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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4850d6b3db63c112574b0ec25b4de8e451981117fc82a90b1b451dad135e4d42' 
  AND token = 'Ld+/UaRe0NGmafrujThRP52mkN/7M3yMS0FGNYqmJwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}