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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f8d25e07d6f5161921ce057a55c610a26bae1207fdd8a349d2b21441a962ed' 
  AND token = '+ekbwpp3PITQ10uSxQXnMdjodpwfJQE48yROB/d4z/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00098

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}