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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0d4b374e14e005fee4c455cee225912676b3375c9c96a0c924fc48b375d104' 
  AND token = 'JWcy5YbWc1JSI7aK+kQTlQ7uc7BCHqYrCWZ7BgrGSoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}