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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721d3f22b0cb7144b1d81e150526cb8c203bb52444f5504e5946c4c805ceb553' 
  AND token = 'HwbrFzUbPlw6e3V5pywK1sF1cmdd9fmnGputfcJdBqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}