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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22447265915f5a268cafed4179924bb2cb77e35241a0b230d1487dbb2d877d59' 
  AND token = 'waD7HNXw3K9WOvJnHE3P8Gw0RulZlZWGln4DZQ8TVHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}