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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '693d76b500770e5c78bdcfc6f8095dd0d4f0a3821ded1ad0f50937ef36d67808' 
  AND token = 'r6cl31bWrNI1yFtN/cLgMhZ3g9yaTPOv+mWjgXyKfE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}