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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde7b8ad4ea74f7e7c3fba4dae5e8a15423f1498ceba9718b8d5befc1be09fac' 
  AND token = '6r7oITGMIGRhCzO+9Gm7/zipSSLxyyrb59VFA+EwzrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}