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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed080b4dddb54be8b14af4a7dd306b62da02580d2bb1c4b5e5cd63e78fa2c624' 
  AND token = 'bH653Q+iGonyFZ6SGrKrZPbIxdrr8zF/ii86a4beDhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}