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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b9b645d8e4995767d3e746161c5b76620851c91b10a235e28aad6d5c853e5e' 
  AND token = 'rpwb8Cn8PU4K9LJqyUjAG4HVdYxi689XKHyGSyTMpJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}